High-Protein Diets May Lead to Atherosclerosis

F. Perry Wilson, MD MSCE
6 min readFeb 21, 2024

And — at least according to this paper — one amino acid is to blame.

Fat, carbohydrate, protein — the three macronutrients that give us the energy we need to live. Macros are a really convenient way to define the major thrust of the diet wars of the last 40 years. From the late 80s low-fat craze — “fat makes you fat”, to the 90s and aughts shift away from carbohydrates in general and sugar in particular, we arrive now to what seems like a fascination with protein.

High-protein diets like the paleo and Zone diets are gaining in popularity. And though the increasingly popular keto diet is really anti-carb more than pro-protein, any diet that limits one macro will inherently increase the concentrations of the others.

It sort of makes some sense that high-protein diets would be good for you. Good stuff inside your body — muscles and stuff — is made of protein and you are what you eat right? But the data doesn’t necessarily support the…

--

--

F. Perry Wilson, MD MSCE
F. Perry Wilson, MD MSCE

Written by F. Perry Wilson, MD MSCE

Medicine, science, statistics. Associate Professor of Medicine and Public Health at Yale. New book “How Medicine Works and When it Doesn’t” available now.

Responses (20)